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Zorluk: OrtaPharmacological and Parenteral Therapies

A nurse is preparing to administer a scheduled dose of 1 gram1 \text{ gram} of intravenous (IV) vancomycin to a client with a severe methicillin-resistant Staphylococcus aureus (MRSA) infection. The pharmacy has dispensed the medication in 250 mL250 \text{ mL} of 0.9%0.9\% sodium chloride. Which action demonstrates safe administration of this parenteral therapy?

  1. Program the IV infusion pump to deliver the medication over a minimum of 6060 minutes.Cevap
  2. B
    Administer the vancomycin through the same IV line as the client's continuous heparin infusion.
  3. C
    Calculate the infusion pump rate to deliver the entire volume rapidly over 3030 minutes.
  4. D
    Obtain a blood sample for a peak serum vancomycin level immediately before starting the infusion.

Cevap

The nurse must program the IV infusion pump to deliver the vancomycin over a minimum of 60 minutes.
Vancomycin is a powerful glycopeptide antibiotic that can cause a histamine-mediated response known as vancomycin infusion reaction (formerly Red Man Syndrome) if administered too rapidly. To ensure patient safety, a dose of 1 gram1 \text{ gram} must be infused over a minimum of 6060 minutes. This prevents sudden severe hypotension, flushing, and a maculopapular rash on the face, neck, and torso.

Adım Adım Çözüm

1
Identify the specific medication and its known administration risks.
Vancomycin is a powerful antibiotic known to cause a severe histamine-mediated response if administered too quickly.
Recognizing drug-specific risks dictates the required administration rate and monitoring parameters.
2
Determine the safest infusion rate for the prescribed dose.
Standard safety protocols require infusing 1 gram1 \text{ gram} of vancomycin over at least 6060 minutes.
A slower infusion rate prevents the histamine release responsible for severe hypotensive infusion reactions.
3
Evaluate the alternative clinical actions for contraindications.
Co-administration with heparin is incompatible, rapid infusion is dangerous, and peak levels are drawn after (not before) the dose.
Eliminating contraindicated actions ensures the selected intervention represents evidence-based safe practice.

Anahtar Kavram

Safe Intravenous Administration of Vancomycin
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