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Zorluk: OrtaPharmacological and Parenteral Therapies

A client admitted with cardiogenic shock requires hemodynamic support. The healthcare provider orders an intravenous infusion of dopamine at a rate of 5 mcg/kg/min5 \text{ mcg/kg/min}. The client's admission weight is 176 lbs176 \text{ lbs}. The pharmacy dispenses a premixed bag containing 400 mg400 \text{ mg} of dopamine in 250 mL250 \text{ mL} of 0.9%0.9\% sodium chloride. At how many mL/hr\text{mL/hr} should the nurse program the infusion pump? (Record answer as a whole number.)

Cevap: 15 mL/hr

Cevap

15
To find the correct infusion rate, first convert the client's weight to kilograms (176÷2.2=80 kg176 \div 2.2 = 80 \text{ kg}). Calculate the dose per minute: 80 kg×5 mcg=400 mcg/min80 \text{ kg} \times 5 \text{ mcg} = 400 \text{ mcg/min}. Convert to an hourly dose: 400 mcg/min×60 min=24,000 mcg/hr400 \text{ mcg/min} \times 60 \text{ min} = 24,000 \text{ mcg/hr}. Find the concentration of the IV bag: 400 mg400 \text{ mg} is 400,000 mcg400,000 \text{ mcg}; 400,000 mcg÷250 mL=1,600 mcg/mL400,000 \text{ mcg} \div 250 \text{ mL} = 1,600 \text{ mcg/mL}. Finally, divide the hourly dose by the concentration to determine the pump rate: 24,000 mcg÷1,600 mcg/mL=15 mL/hr24,000 \text{ mcg} \div 1,600 \text{ mcg/mL} = 15 \text{ mL/hr}.

Adım Adım Çözüm

1
Convert the client's weight from pounds to kilograms.
176 lbs÷2.2 lbs/kg=80 kg176 \text{ lbs} \div 2.2 \text{ lbs/kg} = 80 \text{ kg}
The prescribed dose is weight-based in kg, so the weight must be converted first.
2
Calculate the total dose required per minute.
5 mcg/kg/min×80 kg=400 mcg/min5 \text{ mcg/kg/min} \times 80 \text{ kg} = 400 \text{ mcg/min}
This establishes the exact amount of medication the client needs every minute.
3
Convert the minute dose to an hourly dose.
400 mcg/min×60 min/hr=24,000 mcg/hr400 \text{ mcg/min} \times 60 \text{ min/hr} = 24,000 \text{ mcg/hr}
Infusion pumps are programmed in mL/hr, so the dose must be expressed per hour.
4
Determine the concentration of the available medication in mcg/mL.
400 mg=400,000 mcg400 \text{ mg} = 400,000 \text{ mcg}. Then, 400,000 mcg÷250 mL=1,600 mcg/mL400,000 \text{ mcg} \div 250 \text{ mL} = 1,600 \text{ mcg/mL}
The dose is in mcg, so the medication concentration must also be in mcg to calculate the volume.
5
Calculate the final infusion rate in mL/hr.
24,000 mcg/hr÷1,600 mcg/mL=15 mL/hr24,000 \text{ mcg/hr} \div 1,600 \text{ mcg/mL} = 15 \text{ mL/hr}
Dividing the hourly dose by the concentration yields the volume needed per hour.

Anahtar Kavram

Weight-based continuous intravenous infusion calculations (mcg/kg/min to mL/hr)
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