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Zorluk: Çok zorPharmacological and Parenteral Therapies

A client diagnosed with severe sepsis has a double-lumen central venous catheter (CVC). The proximal lumen is dedicated to a continuous infusion of total parenteral nutrition (TPN). The distal lumen is delivering a continuous infusion of norepinephrine to maintain systemic vascular resistance. During the shift, the client's mean arterial pressure drops to 54 mm Hg54\text{ mm Hg}. The provider verbally prescribes an immediate 500 mL500\text{ mL} intravenous bolus of lactated Ringer's solution and 100 mg100\text{ mg} of hydrocortisone sodium succinate via intravenous push. Which action by the nurse demonstrates the safest administration of these prescribed therapies?

  1. Establish a new peripheral intravenous catheter to administer the fluid bolus and the intravenous push medication.Cevap
  2. B
    Pause the total parenteral nutrition infusion, flush the proximal lumen with sterile saline, and administer the prescribed therapies.
  3. C
    Connect the fluid bolus to the distal lumen and infuse it concurrently with the continuous norepinephrine.
  4. D
    Temporarily pause the norepinephrine, administer the hydrocortisone via the distal lumen, flush the line, and resume the infusion.

Cevap

Establish a new peripheral intravenous catheter to administer the fluid bolus and the intravenous push medication.
The correct answer is to establish a new peripheral intravenous catheter. When managing a critically ill client with a multi-lumen central line, the nurse must adhere to strict parenteral safety rules regardless of the emergency. The proximal lumen is infusing total parenteral nutrition (TPN), which requires a strictly dedicated line; it must never be used for fluid boluses, blood products, or intravenous push medications due to the high risk of infection and chemical incompatibility. The distal lumen is infusing norepinephrine, a potent continuous vasopressor. Connecting a rapid fluid bolus to this line, or flushing the line to administer an intravenous push medication, will rapidly flush the residual norepinephrine residing in the intravenous tubing's dead space directly into the client's central circulation. This unintentional bolus can cause a lethal hypertensive crisis and fatal arrhythmias. Additionally, temporarily pausing the norepinephrine in a severely hypotensive client (MAP of 54 mm Hg) will cause immediate cardiovascular collapse. Therefore, the only safe action is to rapidly establish a new peripheral intravenous access site for the new prescriptions.

Adım Adım Çözüm

1
Evaluate the current utilization and safety constraints of the central venous catheter lumens.
One lumen is dedicated to TPN, and the other is infusing a life-sustaining concentrated vasopressor (norepinephrine).
Safe parenteral administration requires assessing existing access for compatibility, infection control protocols, and hemodynamic safety before administering new emergency therapies.
2
Analyze the clinical safety of using the proximal TPN lumen.
The TPN lumen is strictly rejected for any other uses.
TPN lumens must be exclusively dedicated to parenteral nutrition due to the high risk of central line-associated bloodstream infections (CLABSI) and complex chemical incompatibilities that cause precipitation.
3
Analyze the clinical safety of using the distal vasopressor lumen.
The norepinephrine lumen cannot be used for rapid boluses, nor can it be paused for an intravenous push.
Bolusing fluid or rapidly flushing a line containing a concentrated vasopressor will rapidly force the residual medication in the intravenous tubing (dead space) into the client, causing a potentially lethal spike in blood pressure. Pausing the infusion is also contraindicated as it will immediately worsen the severe hypotensive shock.
4
Determine the safest alternative route for the emergency prescriptions.
A new peripheral intravenous line must be established immediately.
Despite the critical nature of the emergency and the presence of a central line, utilizing inappropriate central lumens poses immediate life-threatening risks. A new access point is the only physiological and pharmacologically safe route.

Anahtar Kavram

Central line lumen dedication, vasopressor administration safety, and the prevention of unintended medication boluses (speed shock).
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