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Zorluk: OrtaPharmacological and Parenteral Therapies

A client with a severe exacerbation of asthma is admitted to the emergency department. The healthcare provider prescribes an intravenous loading dose of aminophylline 5 mg/kg5\text{ mg/kg} to be infused over 30 minutes30\text{ minutes}. The client weighs 154 lbs154\text{ lbs}. The pharmacy dispenses aminophylline 500 mg500\text{ mg} mixed in 500 mL500\text{ mL} of 5%5\% dextrose in water (D5W). At what rate in mL/hr\text{mL/hr} should the nurse program the infusion pump?

Cevap: 700 mL/hr

Cevap

700
To find the correct infusion rate, first convert the weight to kilograms (154 lbs÷2.2=70 kg154\text{ lbs} \div 2.2 = 70\text{ kg}). Next, calculate the dose (70 kg×5 mg/kg=350 mg70\text{ kg} \times 5\text{ mg/kg} = 350\text{ mg}). Since the medication is supplied as 500 mg500\text{ mg} in 500 mL500\text{ mL} (a 1 mg/mL1\text{ mg/mL} concentration), the total volume needed is 350 mL350\text{ mL}. Finally, to find the hourly rate for a 30-minute30\text{-minute} (0.5 hour0.5\text{ hour}) infusion, divide the volume by the time in hours (350 mL÷0.5 hr=700 mL/hr350\text{ mL} \div 0.5\text{ hr} = 700\text{ mL/hr}).

Adım Adım Çözüm

1
Convert the client's weight from pounds to kilograms.
70 kg70\text{ kg}
Weight-based dosages require the client's weight to be expressed in kilograms (154÷2.2=70154 \div 2.2 = 70).
2
Calculate the total required dose of aminophylline in milligrams.
350 mg350\text{ mg}
Multiply the prescribed dose by the client's weight in kilograms (5 mg/kg×70 kg=350 mg5\text{ mg/kg} \times 70\text{ kg} = 350\text{ mg}).
3
Determine the required fluid volume in milliliters to deliver the calculated dose.
350 mL350\text{ mL}
The supplied concentration is 500 mg500\text{ mg} in 500 mL500\text{ mL}, which simplifies to 1 mg/mL1\text{ mg/mL}. Therefore, a 350 mg350\text{ mg} dose is contained in a volume of 350 mL350\text{ mL}.
4
Calculate the infusion pump rate in milliliters per hour (mL/hr\text{mL/hr}).
700 mL/hr700\text{ mL/hr}
The 350 mL350\text{ mL} volume must be infused over 30 minutes30\text{ minutes}, which is 0.5 hours0.5\text{ hours}. Divide the volume by the time in hours to find the hourly rate (350 mL÷0.5 hours=700 mL/hr350\text{ mL} \div 0.5\text{ hours} = 700\text{ mL/hr}).

Anahtar Kavram

Weight-based intravenous medication dosage calculation and infusion pump rate programming.
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Pharmacological and Parenteral Therapies

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