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Zorluk: OrtaPharmacological and Parenteral Therapies

An intensive care nurse is initiating a heparin protocol for a client weighing 80 kg80 \text{ kg} who was recently diagnosed with a pulmonary embolism. The medical prescription indicates a continuous intravenous infusion at 18 units/kg/hr18 \text{ units/kg/hr}. The pharmacy delivers a premixed bag labeled 'Heparin sodium 25,000 units25,000 \text{ units} in 500 mL500 \text{ mL} of 0.45% NaCl0.45\% \text{ NaCl}'. Based on these parameters, how many mL/hr\text{mL/hr} will the infusion pump be programmed to deliver? (Round the final answer to the nearest tenth.)

  1. 28.828.8Cevap
  2. B
    13.113.1
  3. C
    14.414.4
  4. D
    63.463.4

Cevap

The infusion pump should be programmed to deliver 28.8 mL/hr28.8 \text{ mL/hr}.
The correct rate is 28.828.8 because the client requires 1440 units/hr1440 \text{ units/hr} (80 kg×18 units/kg/hr80 \text{ kg} \times 18 \text{ units/kg/hr}), and the available concentration is 50 units/mL50 \text{ units/mL} (25,000 units÷500 mL25,000 \text{ units} \div 500 \text{ mL}). Dividing the required dose by the available concentration (1440÷501440 \div 50) yields exactly 28.8 mL/hr28.8 \text{ mL/hr}.

Adım Adım Çözüm

1
Calculate the total hourly heparin dose required based on the client's weight.
80 kg×18 units/kg/hr=1440 units/hr80 \text{ kg} \times 18 \text{ units/kg/hr} = 1440 \text{ units/hr}
The prescription is weight-based, so the initial step is to determine the absolute number of units needed per hour.
2
Determine the concentration of the available heparin solution.
25,000 units÷500 mL=50 units/mL25,000 \text{ units} \div 500 \text{ mL} = 50 \text{ units/mL}
To calculate the volume to be infused, the amount of medication in each milliliter of the provided bag must be known.
3
Calculate the required infusion rate in mL/hr.
1440 units/hr÷50 units/mL=28.8 mL/hr1440 \text{ units/hr} \div 50 \text{ units/mL} = 28.8 \text{ mL/hr}
Dividing the desired hourly dose by the concentration yields the exact volume to administer per hour.

Anahtar Kavram

Weight-based continuous intravenous medication calculation
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