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Zorluk: KolayPharmacological and Parenteral Therapies

A client is prescribed a scheduled dose of intravenous (IV) phenytoin to manage seizure activity. The client currently has a continuous peripheral IV infusion of 5% dextrose in water (D5W) infusing. Which action must the nurse implement to administer this medication safely?

  1. Flush the intravenous line with 0.9% sodium chloride before and after the administration.Cevap
  2. B
    Administer the medication directly into the lowest Y-port while the continuous infusion remains running.
  3. C
    Push the medication rapidly over 15 to 30 seconds to ensure a quick onset of therapeutic action.
  4. D
    Dilute the medication in a syringe with 10 mL of sterile water prior to injecting it into the line.

Cevap

The correct action is to flush the intravenous line with 0.9% sodium chloride before and after administering the medication.
Phenytoin is highly incompatible with dextrose-containing solutions such as 5% dextrose in water (D5W). If mixed, the medication will quickly precipitate and form crystals. To safely administer the drug through the existing intravenous line, the nurse must clear the dextrose from the tubing by flushing it with a compatible solution—specifically 0.9% sodium chloride (normal saline)—both before and immediately after the medication push.

Adım Adım Çözüm

1
Analyze the compatibility of the prescribed medication with the existing intravenous fluid.
Phenytoin is highly incompatible with dextrose-containing solutions like D5W.
Mixing these two substances causes the phenytoin to form solid precipitates (crystals) in the tubing, which can lead to catheter occlusion or an embolus.
2
Determine the appropriate compatible diluent or flush solution.
Normal saline (0.9% sodium chloride) is the standard and required compatible solution for phenytoin.
Phenytoin remains stable and soluble only in normal saline.
3
Formulate a safe administration sequence using the existing intravenous access.
The nurse must pause the D5W, flush the line with normal saline, administer the drug at the correct rate, and flush again with normal saline before resuming the D5W.
This creates a physical barrier of normal saline between the incompatible medication and the dextrose fluid.

Anahtar Kavram

Intravenous medication compatibility and safe administration principles.
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