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Zorluk: ZorPharmacological and Parenteral Therapies

A client admitted with decompensated heart failure weighing 198 lb198\text{ lb} is prescribed a continuous intravenous infusion of milrinone at 0.5 \mug/kg/min0.5\text{ \mu g/kg/min}. The pharmacy dispenses a premixed bag containing 20 mg20\text{ mg} of milrinone in 100 mL100\text{ mL} of 0.9%0.9\% sodium chloride. The nurse should set the infusion pump to deliver how many mL/hr\text{mL/hr}? (Round the answer to the nearest tenth.)

Cevap: 13.5 mL/hr

Cevap

13.5
To determine the correct infusion rate, a multi-step calculation is required. First, the client's weight is converted to kilograms (198÷2.2=90 kg198 \div 2.2 = 90\text{ kg}). Second, the hourly dose is calculated by multiplying the weight-based dose by the client's weight and then by 6060 minutes (0.5×90×60=2,700 \mug/hr0.5 \times 90 \times 60 = 2,700\text{ \mu g/hr}). Third, the concentration of the IV bag is converted to matching units (20 mg=20,000 \mug20\text{ mg} = 20,000\text{ \mu g}; 20,000÷100 mL=200 \mug/mL20,000 \div 100\text{ mL} = 200\text{ \mu g/mL}). Finally, the hourly dose is divided by the concentration (2,700÷2002,700 \div 200) to yield the correct pump setting of 13.5 mL/hr13.5\text{ mL/hr}.

Adım Adım Çözüm

1
Convert the client's weight from lb to kg.
198 lb÷2.2 lb/kg=90 kg198\text{ lb} \div 2.2\text{ lb/kg} = 90\text{ kg}
The medication dosage is prescribed based on the client's weight in kilograms.
2
Calculate the prescribed dose per minute.
0.5 \mug/kg/min×90 kg=45 \mug/min0.5\text{ \mu g/kg/min} \times 90\text{ kg} = 45\text{ \mu g/min}
This determines the exact amount of milrinone the client needs every minute.
3
Convert the dose per minute to the dose per hour.
45 \mug/min×60 min/hr=2,700 \mug/hr45\text{ \mu g/min} \times 60\text{ min/hr} = 2,700\text{ \mu g/hr}
Intravenous pumps are typically programmed in milliliters per hour (mL/hr), so the hourly dose is required.
4
Determine the concentration of the supplied milrinone solution in \mug/mL\text{\mu g/mL}.
20 mg×1,000 \mug/mg=20,000 \mug20\text{ mg} \times 1,000\text{ \mu g/mg} = 20,000\text{ \mu g}. Then, 20,000 \mug÷100 mL=200 \mug/mL20,000\text{ \mu g} \div 100\text{ mL} = 200\text{ \mu g/mL}
To calculate the volume needed, the medication dose units (micrograms) must match the concentration units.
5
Calculate the infusion rate in mL/hr\text{mL/hr}.
2,700 \mug/hr÷200 \mug/mL=13.5 mL/hr2,700\text{ \mu g/hr} \div 200\text{ \mu g/mL} = 13.5\text{ mL/hr}
Dividing the hourly dose by the concentration yields the fluid volume that needs to be delivered per hour.

Anahtar Kavram

Weight-based continuous intravenous infusion rate calculation requiring multiple unit conversions
Tahmini Süre:3m 0s
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