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Zorluk: OrtaPharmacological and Parenteral Therapies

A critical care nurse is preparing to initiate a continuous IV infusion of dobutamine for a client with severe heart failure. The healthcare provider has prescribed dobutamine at 5 mcg/kg/min5 \text{ mcg/kg/min}. The client weighs 198 lb198 \text{ lb}. The medication is supplied as dobutamine 500 mg500 \text{ mg} in 250 mL250 \text{ mL} of 5% dextrose in water (D5W). At what rate, in mL/hr\text{mL/hr}, should the nurse set the IV infusion pump? (Record your answer using one decimal place.)

Cevap: 13.5 mL/hr

Cevap

13.5
To determine the correct IV pump rate, first convert the weight to kilograms (198 lb÷2.2=90 kg198 \text{ lb} \div 2.2 = 90 \text{ kg}). Then, calculate the total dose in mcg/min (5 mcg/kg/min×90 kg=450 mcg/min5 \text{ mcg/kg/min} \times 90 \text{ kg} = 450 \text{ mcg/min}). Next, convert to an hourly dose (450 mcg/min×60 min/hr=27,000 mcg/hr450 \text{ mcg/min} \times 60 \text{ min/hr} = 27,000 \text{ mcg/hr}), and then to milligrams (27,000 mcg÷1,000=27 mg/hr27,000 \text{ mcg} \div 1,000 = 27 \text{ mg/hr}). Finally, divide the hourly dose by the concentration of the IV bag (500 mg÷250 mL=2 mg/mL500 \text{ mg} \div 250 \text{ mL} = 2 \text{ mg/mL}) to find the rate in mL/hr: 27 mg/hr÷2 mg/mL=13.5 mL/hr27 \text{ mg/hr} \div 2 \text{ mg/mL} = 13.5 \text{ mL/hr}.

Adım Adım Çözüm

1
Convert the client's weight from pounds (lb) to kilograms (kg).
198 lb÷2.2 lb/kg=90 kg198 \text{ lb} \div 2.2 \text{ lb/kg} = 90 \text{ kg}
The prescribed dose is weight-based in kilograms, so the client's weight must first be converted into the correct unit.
2
Calculate the total required dose per minute.
5 mcg/kg/min×90 kg=450 mcg/min5 \text{ mcg/kg/min} \times 90 \text{ kg} = 450 \text{ mcg/min}
Multiplying the prescribed weight-based dose by the client's weight determines the exact dose the client needs each minute.
3
Convert the per-minute dose to an hourly dose.
450 mcg/min×60 min/hr=27,000 mcg/hr450 \text{ mcg/min} \times 60 \text{ min/hr} = 27,000 \text{ mcg/hr}
IV infusion pumps are set in milliliters per hour (mL/hr), so the required medication dose must be calculated on an hourly basis.
4
Convert the hourly dose from micrograms (mcg) to milligrams (mg).
27,000 mcg/hr÷1,000 mcg/mg=27 mg/hr27,000 \text{ mcg/hr} \div 1,000 \text{ mcg/mg} = 27 \text{ mg/hr}
The supplied medication concentration is provided in milligrams, so the requested dose must be converted to match the supplied unit.
5
Calculate the required volume to infuse per hour.
27 mg/hr÷(500 mg/250 mL)=27 mg/hr÷2 mg/mL=13.5 mL/hr27 \text{ mg/hr} \div (500 \text{ mg} / 250 \text{ mL}) = 27 \text{ mg/hr} \div 2 \text{ mg/mL} = 13.5 \text{ mL/hr}
Dividing the desired hourly dose by the medication concentration determines the final infusion pump rate in mL/hr.

Anahtar Kavram

Weight-Based Intravenous Medication Dosage Calculation
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