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Zorluk: OrtaPharmacological and Parenteral Therapies

A healthcare provider prescribes an intravenous infusion of dopamine for a client diagnosed with cardiogenic shock. The prescribed dose is 10 mcg/kg/min10 \text{ mcg/kg/min}. The client weighs 176 lb176 \text{ lb}. The pharmacy dispenses a pre-mixed bag containing 800 mg800 \text{ mg} of dopamine in 250 mL250 \text{ mL} of 5%5\% dextrose in water. The nurse should set the intravenous infusion pump to deliver how many mL/hr? (Record your answer as a whole number).

Cevap: 15 mL/hr

Cevap

15
To safely administer a weight-based continuous intravenous infusion, precise unit conversions for weight (pounds to kilograms), time (minutes to hours), and drug mass (micrograms to milligrams) are necessary. By calculating the hourly required dose (48 mg/hr48 \text{ mg/hr}) and dividing it by the concentration of the dispensed fluid (3.2 mg/mL3.2 \text{ mg/mL}), the correct and safe infusion rate is determined to be 15 mL/hr15 \text{ mL/hr}.

Adım Adım Çözüm

1
Convert the client's weight from pounds to kilograms.
176 lb÷2.2=80 kg176 \text{ lb} \div 2.2 = 80 \text{ kg}
Weight-based medication dosing requires the client's weight to be precisely measured in kilograms.
2
Calculate the total dose required per minute.
80 kg×10 mcg/kg/min=800 mcg/min80 \text{ kg} \times 10 \text{ mcg/kg/min} = 800 \text{ mcg/min}
This establishes the specific therapeutic dose required for this individual client.
3
Convert the dose from per-minute to per-hour.
800 mcg/min×60 min/hr=48,000 mcg/hr800 \text{ mcg/min} \times 60 \text{ min/hr} = 48,000 \text{ mcg/hr}
Standard intravenous infusion pumps are programmed in mL per hour, requiring an hourly drug rate.
4
Convert the required hourly dose from micrograms to milligrams.
48,000 mcg/hr÷1,000 mcg/mg=48 mg/hr48,000 \text{ mcg/hr} \div 1,000 \text{ mcg/mg} = 48 \text{ mg/hr}
The dispensed medication concentration is provided in milligrams; units must match before final calculation.
5
Determine the concentration of the dispensed medication.
800 mg÷250 mL=3.2 mg/mL800 \text{ mg} \div 250 \text{ mL} = 3.2 \text{ mg/mL}
Determining the concentration (mg per single mL) simplifies the calculation of the final fluid volume.
6
Calculate the final infusion rate.
48 mg/hr÷3.2 mg/mL=15 mL/hr48 \text{ mg/hr} \div 3.2 \text{ mg/mL} = 15 \text{ mL/hr}
This yields the exact fluid volume the pump must deliver each hour to administer the prescribed medication dose.

Anahtar Kavram

Weight-based Intravenous Medication Calculations
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