Somatic gene therapy targets non-reproductive cells of the body, and therefore any genetic modifications introduced during the treatment cannot be passed on to the patient's offspring.
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Somatic gene therapy targets non-germline body cells such as bone marrow, liver, or lung tissues. As a result, the therapeutic genetic edits remain confined to the patient and are not passed down to future generations. Inheritable genetic edits are exclusively achieved through germline gene editing.
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Distinction between somatic and germline gene therapy