A 48-year-old woman comes to the office for a routine health maintenance examination. She has a history of rheumatoid arthritis, for which she takes methotrexate and infliximab. She feels well and has no current joint pain, swelling, or systemic symptoms. Her last preventive care visit was 2 years ago, during which she underwent a screening colonoscopy that was normal. At that same visit, she had a normal Papanicolaou (Pap) test with negative high-risk human papillomavirus (HPV) testing. A fasting lipid panel and hemoglobin A1c obtained 1 month ago by her rheumatologist were within normal limits. She reached menarche at age 12 and has regular, monthly menstrual cycles with no abnormal bleeding. Her mother was diagnosed with endometrial cancer at age 65 and breast cancer at age 62. Vital signs are within normal limits, and her BMI is . Physical examination, including a clinical breast examination, reveals no masses or skin changes. Which of the following is the most appropriate next step in preventive care for this patient?
- AEndometrial biopsy
- BRoutine measurement of serum thyrotropin (TSH) level
- Biennial screening mammographyCevap
- DAdministration of live-attenuated influenza vaccine
- EAnnual screening breast magnetic resonance imaging (MRI)