A 15-month-old male toddler is evaluated in the pediatric emergency center due to worsening respiratory effort and poor oral intake over the last 24 hours. The parents note that he developed a profuse runny nose, mild fever, and a paroxysmal cough three days ago. His birth history is notable for delivery at 34 weeks gestation. He has no history of atopy or prior wheezing episodes. On physical examination, the patient's temperature is (), heart rate is , respiratory rate is , and oxygen saturation is on room air. The child appears lethargic but is easily arousable. He exhibits pronounced nasal flaring, intercostal retractions, and expiratory grunting. Auscultation of the chest reveals widespread coarse crackles and high-pitched expiratory polyphonic wheezing. Which of the following interventions are indicated as part of the most appropriate management bundle for this patient? (Select all that apply)
- Initiation of heated humidified high-flow nasal cannula or supplemental oxygenCevap
- Establishment of enteral or intravenous fluid resuscitationCevap
- CDelivery of inhaled bronchodilator therapy
- DInitiation of systemic glucocorticoids
- EInitiation of empiric intravenous ceftriaxone