A 72-year-old retired teacher presents to the urgent care clinic with progressively worsening breathing difficulty over the past three days. He reports a sensation of chest tightness and a new cough that produces clear, frothy sputum. His medical history includes hypertension, coronary artery disease, and a 35-pack-year smoking history, though he quit five years ago. Over the last two nights, he has frequently awakened gasping for air and has resorted to sleeping upright in a recliner chair. His current home medications are aspirin, metoprolol, and lisinopril. Vital signs are temperature 36.8°C (98.2°F), blood pressure 168/94 mm Hg, pulse 110/min, and respiratory rate 24/min. Pulse oximetry is 88% on room air. Physical examination reveals prominent jugular venous distention. Lung auscultation demonstrates widespread expiratory wheezing and fine crackles extending to the mid-lung fields bilaterally. Cardiac examination reveals tachycardia with a regular rhythm and an extra low-frequency heart sound occurring just after S2. There is 2+ bilateral pitting edema extending to the mid-calf. Which of the following is the most appropriate initial pharmacologic management for this patient?
- AInhaled albuterol
- BOral azithromycin
- Intravenous furosemideCevap
- DIntravenous methylprednisolone
- EInhaled tiotropium