A comprehensive infertility evaluation requires selecting targeted diagnostic investigations based on the patient's specific clinical history and physical examination findings. Match each suspected etiology of female infertility with its most appropriate initial diagnostic investigation or biomarker.
- Suspected fallopian tube occlusion secondary to prior pelvic inflammatory diseaseHysterosalpingography
- Suspected decline in oocyte quantity in a woman of advanced maternal ageAnti-Müllerian hormone (AMH) measurement
- Suspected anatomic defect of the uterine cavity, such as a submucosal leiomyomaSaline infusion sonohysterography
- Suspected pituitary adenoma presenting with amenorrhea and galactorrheaSerum prolactin measurement
Cevap
The correct pairings are: 1) Fallopian tube occlusion matches with Hysterosalpingography; 2) Decline in oocyte quantity matches with Anti-Müllerian hormone (AMH) measurement; 3) Anatomic defect of the uterine cavity matches with Saline infusion sonohysterography; 4) Pituitary adenoma matches with Serum prolactin measurement.
Each infertility etiology requires a specific diagnostic modality based on whether the underlying issue is structural or endocrine. Structural tubal issues are assessed with contrast imaging (hysterosalpingography), the ovarian follicle pool is measured via hormone levels reflecting granulosa cell output (AMH), uterine cavity defects are evaluated by fluid-distended ultrasound (saline infusion sonohysterography), and endocrine anovulation presenting with galactorrhea is diagnosed with serum prolactin levels.
Adım Adım Çözüm
Anahtar Kavram
Selecting the appropriate initial investigation for specific etiologies of female infertility