Review the brief patient descriptions below. Match each clinical scenario with its most likely hematologic diagnosis.
- A 65-year-old man presents with painless cervical lymphadenopathy. Peripheral smear shows numerous small, mature-appearing lymphocytes and several fragmented cells (smudge cells).Chronic lymphocytic leukemia
- A 28-year-old woman develops sudden, severe bleeding from her gums and venipuncture sites. Bone marrow biopsy reveals immature myeloid cells containing numerous needle-like eosinophilic cytoplasmic inclusions.Acute promyelocytic leukemia
- A 22-year-old man presents with a painless supraclavicular lymph node that becomes painful shortly after drinking alcohol. Lymph node biopsy demonstrates large, binucleated cells with prominent nucleoli.Hodgkin lymphoma
- A 19-year-old man develops jaundice and dark urine two days after starting treatment with sulfamethoxazole-trimethoprim. Peripheral smear reveals cells with semicircular peripheral defects.Glucose-6-phosphate dehydrogenase deficiency
Cevap
The correct pairings connect highly specific pathognomonic clinical presentations and microscopic findings with their respective hematologic disorders.
Each clinical scenario contains classic, pathognomonic findings that correspond directly to a specific hematologic disorder. Recognizing these specific associations is key to arriving at the correct diagnosis for each patient presentation.
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Diagnosis of classic hematologic and oncologic disorders relies heavily on recognizing pathognomonic microscopic findings and specific clinical triggers.
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