A 45-year-old woman is brought to the emergency department after being thrown from a horse. She was wearing a helmet but landed forcefully on her back. Upon arrival, she is immobilized on a rigid backboard with a cervical collar. She is conscious and alert but reports an inability to move her legs and a lack of sensation below her chest. Vital signs reveal a blood pressure of mmHg, a heart rate of /min, and a respiratory rate of /min. Oxygen saturation is on room air. Physical examination demonstrates warm, flushed skin in the upper and lower extremities. Pulses are bounding. Which of the following is the most likely etiology of this patient's hemodynamic findings?
- Disruption of descending sympathetic pathwaysCevap
- BAcute hemorrhage into the retroperitoneal cavity
- CAccumulation of pressurized air in the pleural space
- DRapid accumulation of blood in the pericardial sac
- ESystemic inflammatory response to an invasive pathogen
Cevap
Disruption of descending sympathetic pathways
This patient's presentation of hypotension, bradycardia, and warm extremities following significant spinal trauma (paraplegia, loss of sensation) is classic for neurogenic shock. Spinal cord injury above the level of T1-T4 can disrupt descending sympathetic pathways. This leads to a loss of sympathetic vascular tone, resulting in massive peripheral vasodilation (causing hypotension and warm, flushed skin). Furthermore, the loss of sympathetic innervation to the heart leaves parasympathetic (vagal) tone unopposed, preventing the expected compensatory tachycardia and instead causing bradycardia.
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Anahtar Kavram
Neurogenic shock is characterized by hypotension, bradycardia, and warm extremities due to the loss of sympathetic vascular tone following a spinal cord injury.
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