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Zorluk: KolayMeasures of Disease Frequency and Association

A local health department investigates an outbreak of a novel skin rash in an agricultural community. Officials enroll a cohort of 2,0002,000 residents and follow them over a 33-month period. Among the 500500 residents who work directly with a newly introduced pesticide, 100100 develop the rash. Among the 1,5001,500 residents who do not work with the pesticide, 150150 develop the rash. Which of the following is the relative risk of developing the rash associated with pesticide exposure?

  1. A
    0.10.1
  2. B
    0.50.5
  3. 2.02.0Cevap
  4. D
    2.252.25
  5. E
    10.010.0

Cevap

The relative risk is 2.02.0.
The relative risk (RR) is calculated by dividing the incidence of the disease in the exposed group by the incidence in the unexposed group. The incidence in the exposed group is 100/500=0.20100 / 500 = 0.20. The incidence in the unexposed group is 150/1,500=0.10150 / 1,500 = 0.10. Therefore, the relative risk is 0.20/0.10=2.00.20 / 0.10 = 2.0. This indicates that individuals exposed to the pesticide are twice as likely to develop the rash compared to those unexposed.

Adım Adım Çözüm

1
Calculate the incidence of the rash in the exposed group.
100/500=0.20100 / 500 = 0.20
Incidence is the number of new cases divided by the population at risk in that specific group.
2
Calculate the incidence of the rash in the unexposed group.
150/1,500=0.10150 / 1,500 = 0.10
This establishes the baseline risk for those without the pesticide exposure.
3
Calculate the relative risk by dividing the incidence in the exposed by the incidence in the unexposed.
0.20/0.10=2.00.20 / 0.10 = 2.0
Relative risk compares the likelihood of disease between two groups in a cohort study.

Anahtar Kavram

Relative risk (RR) is the measure of association used in cohort studies, calculated as the incidence of disease in the exposed group divided by the incidence in the unexposed group.
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