A female infant born at 26 weeks gestation is evaluated in the neonatal intensive care unit on day 16 of life. The nursing staff notes that she has become increasingly lethargic over the last 6 hours and has had multiple episodes of apnea and bradycardia. She has been tolerating small volumes of expressed breast milk via an orogastric tube. Vital signs show a temperature of 35.1°C (95.2°F), heart rate of 178/min, and blood pressure of 42/22 mm Hg. Physical examination reveals a tense, shiny, and grossly distended abdomen with absent bowel sounds. Capillary refill time is 4 seconds. Laboratory studies demonstrate a leukocyte count of 3,200/mm³ and a serum bicarbonate of 11 mEq/L. A supine anteroposterior abdominal radiograph displays air in the bowel wall and a distinct area of radiolucency outlining the falciform ligament. Which of the following is the most appropriate next step in management?
- ADiscontinue enteral feeds, insert an orogastric tube, and start broad-spectrum intravenous antibiotics
- BComputed tomography scan of the abdomen
- Immediate exploratory laparotomyCevap
- DAdminister intravenous sodium bicarbonate
- ESwitch enteral feeds to a hypoallergenic, hydrolyzed formula