A 9-year-old boy is brought to the emergency department via ambulance for severe difficulty breathing. His parents report that his symptoms began hours ago with a cough and wheezing, and worsened significantly over the past hours. He has a history of moderate persistent asthma and has been using his albuterol inhaler every hour for the past hours without relief. He is fully immunized. On arrival, the patient is agitated, diaphoretic, and speaking in single words. His temperature is (), blood pressure is , pulse is , and respirations are . Pulse oximetry shows on room air. Physical examination reveals marked suprasternal and subcostal retractions. Lung auscultation reveals diminished air entry bilaterally with a prolonged expiratory phase and faint, high-pitched expiratory wheezing. Arrange the following interventions in the most appropriate sequence of administration for this patient's acute management.
- 1Apply supplemental oxygen via non-rebreather mask
- 2Administer continuous nebulized albuterol and ipratropium bromide
- 3Administer intravenous methylprednisolone
- 4Administer intravenous magnesium sulfate
- 5Prepare for endotracheal intubation or noninvasive positive-pressure ventilation