A -year-old woman is evaluated in the clinic due to progressive fatigue, constant chilling, and a -kg (-lb) weight gain over the past months. She also reports worsening shortness of breath when climbing stairs, frequent morning headaches, and a tendency to bump into objects on her sides. She has not had a menstrual period in months. Her medical history is unremarkable, and she takes no medications. Vital signs show a temperature of C ( F), blood pressure of mmHg, pulse of /min, and respiratory rate of /min. Physical examination reveals a lethargic, pale woman with a delayed relaxation phase of the deep tendon reflexes. Visual field testing reveals bitemporal hemianopsia. She has non-pitting edema of the bilateral lower extremities. The lungs are clear to auscultation.
Laboratory studies reveal:
Sodium: mEq/L
Potassium: mEq/L
Creatinine: mg/dL
Thyroid-stimulating hormone (TSH): U/mL (Normal: – U/mL)
Free thyroxine (T4): ng/dL (Normal: – ng/dL)
Which of the following is the most appropriate next step in management?
- AInitiation of daily oral levothyroxine
- Measurement of serum cortisol levelCevap
- CAdministration of intravenous furosemide
- DArterial blood gas analysis
- EInitiation of empiric broad-spectrum antibiotics