During routine rounding in the neonatal intensive care unit, a physician evaluates a male newborn delivered minutes ago via elective cesarean section at weeks of gestation. The mother's pregnancy was complicated by diet-controlled gestational diabetes. The infant, weighing , had Apgar scores of and at and minutes, respectively. He was admitted to the unit for close monitoring due to increased work of breathing. Current vital signs show a temperature of (), pulse of , and respirations of . He is maintaining an oxygen saturation of on continuous positive airway pressure (CPAP). Physical examination reveals mild intercostal retractions. Detailed skin inspection shows scattered, non-erythematous, superficial vesicles and small pustules over the chin, neck, and lower back. Several of these lesions have ruptured, leaving a collarette of scale surrounding a flat, hyperpigmented macule. Laboratory evaluation reveals a leukocyte count of with a normal differential. A Wright-stained smear of fluid from an intact pustule demonstrates numerous neutrophils and no bacteria. Chest radiography displays increased lung volumes, prominent perihilar vascular markings, and fluid in the minor fissure. Which of the following is the most appropriate next step in management?
- AInitiate intravenous ampicillin and gentamicin
- BInitiate intravenous acyclovir
- Continue continuous positive airway pressure and observationCevap
- DInitiate topical mupirocin therapy
- EAdminister intravenous fluconazole