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Zorluk: OrtaCardiothoracic and Vascular Surgery

A 74-year-old retired teacher is evaluated in the emergency department for sudden, excruciating pain in his right lower extremity that began 3 hours ago. He reports that his foot feels cold and he cannot move his toes. His past medical history includes hypertension, osteoarthritis, and paroxysmal atrial fibrillation. He is not currently taking anticoagulation due to a history of peptic ulcer disease. His pulse is 112/min and irregularly irregular, and his blood pressure is 152/88 mm Hg. Physical examination reveals a pale, cold right leg from the mid-calf distally. The right femoral pulse is palpable, but the popliteal and pedal pulses are absent. There is profound sensory loss over the dorsum of the foot, and the patient is unable to actively dorsiflex his ankle. Continuous-wave Doppler ultrasound detects venous signals but no arterial signals over the dorsalis pedis artery. Which of the following is the most appropriate next step in management?

  1. Intravenous heparin administration and emergent surgical embolectomyCevap
  2. B
    Catheter-directed intra-arterial thrombolysis
  3. C
    Computed tomography angiography of the right lower extremity
  4. D
    Immediate four-compartment fasciotomy of the right leg
  5. E
    Oral rivaroxaban administration and elevation of the extremity

Cevap

Intravenous heparin administration and emergent surgical embolectomy
This patient's presentation of sudden-onset right leg pain, pallor, pulselessness, sensory loss, and inability to dorsiflex the ankle is highly characteristic of acute limb ischemia (ALI). Given his history of atrial fibrillation without anticoagulation, the likely etiology is an arterial embolus. The presence of neurologic deficits (sensory loss and motor weakness) classifies this as a Rutherford category IIb (immediately threatened) limb. For an immediately threatened limb, the most appropriate management is prompt systemic anticoagulation with intravenous heparin (to prevent clot propagation) followed immediately by surgical revascularization (e.g., surgical thromboembolectomy). Delaying surgical revascularization in a category IIb patient will likely lead to irreversible tissue necrosis and subsequent amputation.

Adım Adım Çözüm

1
Evaluate the clinical presentation of the painful, pale, pulseless, and cold extremity.
Identifies acute limb ischemia (ALI) secondary to a presumed arterial thromboembolism from atrial fibrillation.
The sudden onset and the classic '6 Ps' (pain, pallor, poikilothermia, pulselessness, paresthesia, paralysis) are the hallmark signs of acute arterial occlusion.
2
Determine the severity of the ischemia using clinical findings.
The patient is classified as having Rutherford category IIb (immediately threatened) ischemia.
The presence of significant sensory loss and muscle weakness (inability to dorsiflex the ankle) indicates impending irreversible tissue damage.
3
Select the most appropriate management for an immediately threatened limb.
Immediate systemic anticoagulation and surgical revascularization.
Category IIb ischemia requires emergent surgical embolectomy because time-consuming therapies like thrombolysis will take too long, resulting in permanent limb loss.

Anahtar Kavram

Management of acute limb ischemia based on Rutherford classification
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