During a new patient evaluation, a 34-year-old female is noted to have a blood pressure of mm Hg. She returns to the clinic two weeks later for a follow-up, and her blood pressure is mm Hg. The patient reports feeling entirely well, with no headaches, palpitations, or muscle weakness. She has no known medical conditions and takes no medications or over-the-counter supplements. She does not use tobacco or illicit substances. Her body mass index is kg/m . Physical examination reveals normal pulses in all extremities and no abdominal bruits. A comprehensive metabolic panel is obtained to assess baseline organ function, demonstrating a serum sodium of mEq/L, serum potassium of mEq/L, serum chloride of mEq/L, serum bicarbonate of mEq/L, and serum creatinine of mg/dL. Which of the following is the most appropriate next step in the diagnostic workup for this patient?
- Measurement of plasma aldosterone concentration and plasma renin activityCevap
- BComputed tomography of the adrenal glands
- CIntravenous saline infusion test
- DRenal artery duplex ultrasonography
- EInitiation of chlorthalidone therapy