A -year-old woman presents to the outpatient cardiology office for evaluation of chest discomfort. Over the past month, she has experienced multiple episodes of a dull, left-sided chest ache that consistently occurs when climbing the two flights of stairs to her apartment. The pain reliably resolves after minutes of rest. She has a history of type 2 diabetes mellitus, hypertension, and chronic kidney disease stage 4. Her current medications include amlodipine, lisinopril, and insulin glargine.
Vital signs are temperature C ( F), blood pressure mmHg, heart rate /min, and respiratory rate /min. Physical examination reveals a normal point of maximal impulse, normal and , and no murmurs or gallops. Lungs are clear to auscultation. There is no lower extremity edema.
Recent laboratory studies show:
| Test | Result |
|---|---|
| Hemoglobin | g/dL |
| Creatinine | mg/dL |
| eGFR | mL/min/ |
| Hemoglobin A1c |
A resting -lead electrocardiogram shows sinus rhythm with a QRS duration of ms, broad notched R waves in leads I, aVL, , and , and deep S waves in leads and . No prior electrocardiograms are available for comparison.
Which of the following is the most appropriate next step in the diagnostic workup for this patient's chest pain?
- Pharmacologic stress testing with a vasodilator and myocardial perfusion imagingCevap
- BPharmacologic stress testing with dobutamine echocardiography
- CExercise treadmill electrocardiography
- DCoronary computed tomography angiography
- EInvasive coronary angiography