A 72-year-old man presents to the emergency department with sudden, severe pain in his left lower leg that began 2 hours ago. He has a history of permanent atrial fibrillation but reports running out of his prescribed oral anticoagulant medication three weeks ago. On physical examination, his left foot and calf are pale and cool to the touch. The left femoral pulse is palpable, but the popliteal, dorsalis pedis, and posterior tibial pulses are absent to palpation and inaudible on continuous-wave Doppler ultrasound. Sensation is markedly decreased over the dorsum of the foot, and the patient is unable to move his toes. The right lower extremity is warm with strong distal pulses. Which of the following interventions are indicated for the immediate management of this patient? (Select all that apply)
- Initiation of a continuous intravenous unfractionated heparin infusionCevap
- Urgent open surgical thromboembolectomyCevap
- CComputed tomography angiography of the lower extremities
- DCatheter-directed intra-arterial thrombolysis
- EObservation with sequential Doppler ultrasound examinations