A 68-year-old man is brought to the emergency department by his daughter due to worsening shortness of breath and progressive lethargy over the past 6 hours. He has a medical history of severe chronic obstructive pulmonary disease and heart failure with preserved ejection fraction. On arrival, the patient is somnolent, only minimally responsive to loud verbal stimuli, and is noted to have a weak gag reflex. His temperature is 37.4°C (99.3°F), heart rate is 118/min, blood pressure is 152/88 mmHg, respiratory rate is 34/min with shallow efforts, and oxygen saturation is 76% on room air. Physical examination reveals profound use of accessory muscles of respiration, diaphoresis, and diminished breath sounds bilaterally with faint expiratory wheezes. Which of the following is the most urgent initial step in the management of this patient?
- Endotracheal intubationCevap
- BArterial blood gas analysis
- CNoninvasive positive pressure ventilation
- DComputed tomography angiography of the chest
- EImmediate transfer to the medical intensive care unit