An outpatient consultation is arranged for a -year-old male due to a five-week history of significant weight loss, constant resting tremor, and profound heat intolerance. He has a known history of severe ischemic cardiomyopathy with a left ventricular ejection fraction of , as well as recurrent sustained ventricular tachycardia for which an implantable cardioverter-defibrillator was placed two years ago. His medication regimen includes lisinopril, metoprolol succinate, spironolactone, and amiodarone. He has been taking amiodarone consistently for the past months.
Vital signs show a temperature of (), blood pressure of , and an irregular heart rate of . Physical examination reveals a fine tremor of the outstretched hands and a hyperdynamic precordium. The thyroid gland is normal in size, non-tender, and without palpable nodules.
Laboratory studies reveal:
Thyroid-stimulating hormone (TSH):
Free thyroxine (T4): (Reference: )
Total triiodothyronine (T3): (Reference: )
A color flow Doppler ultrasonography of the anterior neck demonstrates a structurally normal thyroid gland with markedly reduced vascularity.
Which of the following is the most appropriate next step in the management of this patient's thyroid dysfunction?
- Initiate high-dose oral prednisoneCevap
- BPrescribe oral methimazole
- CDiscontinue amiodarone therapy and recheck thyroid function in four weeks
- DRefer the patient for radioactive iodine ablation
- EAdminister potassium perchlorate