A 65-year-old man presents to the ambulatory care office for a follow-up visit one week after being diagnosed with nonvalvular atrial fibrillation. His past medical history is also significant for severe chronic obstructive pulmonary disease. At his previous visit, he was prescribed apixaban for stroke prevention based on a CHA DS -VASc score of 3. Today, the patient states, "I prefer to avoid synthetic medications whenever possible. I have been taking an over-the-counter St. John's wort supplement for the past year to help with occasional sadness. I would rather just take my supplement along with a daily aspirin instead of this new prescription." The patient is alert, fully oriented, and accurately describes the risks of untreated atrial fibrillation, but he expresses a strong personal distrust of pharmaceutical companies. Which of the following is the most appropriate physician response to educate and counsel this patient?
- St. John's wort can decrease the effectiveness of apixaban, increasing your risk of a stroke. Can we discuss your specific concerns about the new medication?Cevap
- BBecause your condition carries a high risk of stroke, choosing to decline the recommended treatment indicates a lack of capacity to refuse care.
- CSince you are 65 years old, substituting the new medication with daily low-dose aspirin satisfies the preventive guidelines for stroke reduction.
- DSt. John's wort is generally safe to take with apixaban; you may continue your current regimen as long as you attend regular follow-up visits.
- EWe can switch your medication to a non-selective beta-blocker to prevent strokes, which avoids any interactions with your herbal supplement.