During a routine follow-up visit, a retired construction worker with a 15-year history of poorly controlled type 2 diabetes mellitus asks the physician to evaluate a wound on the bottom of his right foot. He noticed a foul-smelling discharge on his sock earlier this week but denies any pain, fever, or chills. Vital signs are within normal limits. Examination of the right plantar aspect reveals a 3 cm by 2 cm deep ulceration under the first metatarsal head. The ulcer is surrounded by a 2-cm rim of erythema and warmth. Dorsalis pedis and posterior tibial pulses are 2+ bilaterally. Probing the base of the ulcer with a sterile blunt instrument reveals a hard, gritty surface. Which of the following diagnostic steps are indicated as the most appropriate initial evaluation for this patient's current condition? (Select 2)
- Plain radiography of the affected footCevap
- Serum erythrocyte sedimentation rate and C-reactive protein levelsCevap
- CMagnetic resonance imaging of the affected foot
- DSuperficial swab culture of the purulent discharge
- ETechnetium-99m three-phase bone scintigraphy