A 65-year-old man is urgently evaluated by the rapid response team due to sudden-onset hypotension and altered mental status. Two days ago, he underwent an open right hemicolectomy for colon adenocarcinoma. Earlier this morning, he developed acute dyspnea; a computed tomography pulmonary angiogram confirmed a segmental pulmonary embolism, and a therapeutic continuous intravenous heparin infusion was initiated. He now appears lethargic, pale, and diaphoretic. His temperature is 37.0°C (98.6°F), blood pressure is 76/45 mm Hg, pulse is 134/min, and respirations are 24/min. Physical examination reveals a newly distended, firm, and diffusely tender abdomen. The surgical wound is intact with no external bleeding. Laboratory testing shows a hemoglobin level of 6.2 g/dL, representing a significant drop from 11.4 g/dL drawn 8 hours prior. Which of the following is the most appropriate next step in the management of this patient?
- Discontinue the heparin infusion, initiate volume resuscitation, and prepare for an emergent exploratory laparotomyCevap
- BAdminister intravenous alteplase to treat presumed massive pulmonary embolism
- CTransfer the patient to the radiology suite for a computed tomography scan of the abdomen and pelvis
- DPerform a bedside transthoracic echocardiogram to evaluate for acute right ventricular failure
- EAdminister a platelet transfusion to promote hemostasis while continuing medical therapy for the pulmonary embolism