Question

Difficulty: MediumMendel's Second Law and Dihybrid Inheritance

In guinea pigs (*Cavia porcellus*), black coat color (BB) is dominant over white coat color (bb), and short hair (SS) is dominant over long hair (ss). If two heterozygous guinea pigs (BbSsBbSs) are mated and produce a total of 400400 offspring, how many offspring are expected to display the black coat and long hair phenotype?

Answer: 75 offspring

Answer

75 offspring are expected to display the black coat and long hair phenotype.
In a dihybrid cross between two individuals heterozygous for both traits (BbSs×BbSsBbSs \times BbSs), independent assortment produces an F2F_2 phenotypic ratio of 9:3:3:19:3:3:1. The phenotype with one dominant and one recessive trait (black coat and long hair, B_ssB\_ss) represents 316\frac{3}{16} of the total offspring population. Out of 400400 offspring, the expected count is calculated as 316×400=75\frac{3}{16} \times 400 = 75.

Step-by-Step Solution

1
Determine the phenotypic ratio from the dihybrid cross BbSs×BbSsBbSs \times BbSs.
The expected ratio is 9:3:3:19 : 3 : 3 : 1 for (black coat, short hair) : (black coat, long hair) : (white coat, short hair) : (white coat, long hair).
Mendel's Law of Independent Assortment dictates that the two gene pairs segregate independently during gamete formation.
2
Determine the proportion of offspring showing the black coat and long hair phenotype (B_ssB\_ss).
The proportion is 316\frac{3}{16}.
The probability of inheriting the dominant coat trait (B_B\_) is 34\frac{3}{4}, and the probability of inheriting the recessive hair length trait (ssss) is 14\frac{1}{4}. Combined probability = 34×14=316\frac{3}{4} \times \frac{1}{4} = \frac{3}{16}.
3
Multiply the proportion by the total population size to find the expected number of offspring.
316×400=75\frac{3}{16} \times 400 = 75.
Applying the theoretical phenotypic probability to the sample size of 400 yields the expected count.

Key Concept

Mendel's Law of Independent Assortment and Dihybrid Phenotypic Ratios
Estimated Time:1m 30s
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