Question

Difficulty: MediumPharmacological Therapies

A practical nurse (PN) in a pediatric clinic is preparing to administer the first dose of oral amoxicillin to a toddler diagnosed with acute otitis media. The toddler weighs 33 lbs33\text{ lbs}. The primary healthcare provider has prescribed 45 mg/kg/day45\text{ mg/kg/day} of amoxicillin, to be administered in two equally divided doses every 12 hours12\text{ hours}. The clinic pharmacy dispenses amoxicillin oral suspension at a concentration of 250 mg/5 mL250\text{ mg}/5\text{ mL}. How many milliliters (mL\text{mL}) should the PN administer for this single dose? Record your answer to the nearest tenth. Do not include units in your answer.

Answer: 6.8 mL

Answer

6.8
To determine the correct dose, first convert the weight to kilograms (33 lbs÷2.2=15 kg33\text{ lbs} \div 2.2 = 15\text{ kg}). Next, calculate the daily dose (15 kg×45 mg/kg=675 mg/day15\text{ kg} \times 45\text{ mg/kg} = 675\text{ mg/day}). Divide by 2 for the single dose every 12 hours (337.5 mg/dose337.5\text{ mg/dose}). Finally, use the desired-over-have formula: (337.5 mg÷250 mg)×5 mL=6.75 mL(337.5\text{ mg} \div 250\text{ mg}) \times 5\text{ mL} = 6.75\text{ mL}, which rounds up to 6.8 mL6.8\text{ mL}.

Step-by-Step Solution

1
Convert the client's weight from pounds to kilograms.
15 kg15\text{ kg}
Weight-based dosing requires the body weight to be calculated in kilograms.
2
Calculate the total daily dose prescribed.
675 mg/day675\text{ mg/day}
The prescription is written as a total daily amount based on the child's weight.
3
Determine the amount for a single dose.
337.5 mg/dose337.5\text{ mg/dose}
The medication is to be administered in two equally divided doses every 12 hours.
4
Calculate the liquid volume to administer for one dose.
6.75 mL6.75\text{ mL}
This calculation uses the available pharmacy concentration of 250 mg/5 mL250\text{ mg}/5\text{ mL} to find the required volume.
5
Round the final answer to the nearest tenth.
6.8 mL6.8\text{ mL}
Clinical calculations are typically rounded to the nearest tenth for volumes greater than 1 mL1\text{ mL} to ensure safe and accurate measurement.

Key Concept

Pediatric Weight-Based Dosage Calculation
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