Question

Difficulty: MediumPharmacological Therapies

A client weighing 198 lb198\text{ lb} is prescribed enoxaparin sodium 1 mg/kg1\text{ mg/kg} subcutaneously every 12 hours for the treatment of a deep vein thrombosis. The medication is supplied as a prefilled syringe containing 120 mg120\text{ mg} in 0.8 mL0.8\text{ mL}. How many milliliters (mL\text{mL}) should the practical nurse administer for a single dose?

(Record the answer to the nearest tenth. Do not include units in the answer.)

Answer: 0.6 mL

Answer

0.6
To determine the correct volume to administer, the nurse must first convert the client's weight to kilograms: 198 lb÷2.2=90 kg198\text{ lb} \div 2.2 = 90\text{ kg}. Next, the desired dose is calculated by multiplying the weight by the prescribed amount: 90 kg×1 mg/kg=90 mg90\text{ kg} \times 1\text{ mg/kg} = 90\text{ mg}. Finally, the volume is calculated using the formula (Desired / Have) ×\times Volume: (90 mg÷120 mg)×0.8 mL=0.6 mL(90\text{ mg} \div 120\text{ mg}) \times 0.8\text{ mL} = 0.6\text{ mL}.

Step-by-Step Solution

1
Convert the client's weight from pounds to kilograms
90 kg
The medication is prescribed based on the client's weight in kilograms.
2
Calculate the total required dose per administration
90 mg
Multiply the client's weight in kilograms by the prescribed dosage of 1 mg/kg.
3
Determine the liquid volume to administer
0.6 mL
Divide the desired dose (90 mg) by the available concentration (120 mg), then multiply by the supplied volume (0.8 mL).

Key Concept

Weight-based parenteral medication dosage calculation
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