Question

Difficulty: MediumPharmacological Therapies

An adult client admitted with a severe gastrointestinal infection is prescribed metronidazole oral suspension. The prescription directs the administration of 7.5 mg/kg7.5 \text{ mg/kg} every 6 hours6 \text{ hours}. The client's documented weight is 154 lb154 \text{ lb}. The pharmacy supplies the medication with a label reading 250 mg/5 mL250 \text{ mg}/5 \text{ mL}. How many mL\text{mL} should the practical nurse administer for a single dose? Record your answer to the nearest tenth. Do not include units in your answer.

Answer: 10.5 mL

Answer

The practical nurse should administer 10.5 mL.
The correct volume is 10.5 mL10.5 \text{ mL}. To find this, the nurse must first convert the weight from pounds to kilograms (154÷2.2=70 kg154 \div 2.2 = 70 \text{ kg}). Next, determine the ordered dose by multiplying the weight by the prescription (70 kg×7.5 mg/kg=525 mg70 \text{ kg} \times 7.5 \text{ mg/kg} = 525 \text{ mg}). Finally, calculate the volume using the ratio of the available medication: (525 mg÷250 mg)×5 mL=10.5 mL(525 \text{ mg} \div 250 \text{ mg}) \times 5 \text{ mL} = 10.5 \text{ mL}.

Step-by-Step Solution

1
Convert the client's weight from pounds to kilograms.
154 lb÷2.2 lb/kg=70 kg154 \text{ lb} \div 2.2 \text{ lb/kg} = 70 \text{ kg}
The prescribed medication is dosed based on the client's weight in kilograms.
2
Calculate the total required dose in milligrams.
70 kg×7.5 mg/kg=525 mg70 \text{ kg} \times 7.5 \text{ mg/kg} = 525 \text{ mg}
This determines the exact amount of medication the client needs per dose based on the order.
3
Calculate the volume of liquid to administer in milliliters.
(525 mg250 mg)×5 mL=10.5 mL(\frac{525 \text{ mg}}{250 \text{ mg}}) \times 5 \text{ mL} = 10.5 \text{ mL}
This determines how much of the supplied concentration is needed to deliver the required dose.

Key Concept

Weight-based medication dosage calculation and liquid concentration conversion
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