Question

Difficulty: MediumPharmacological Therapies

While reviewing the electronic health record of a client diagnosed with a severe infection, a practical nurse observes a significant change in the client's laboratory results. The morning serum creatinine has increased to 2.9 mg/dL (reference range: 0.6–1.2 mg/dL) from a baseline of 1.0 mg/dL upon admission. The client is prescribed intravenous gentamicin, and the next dose is scheduled to be administered in 15 minutes. Which action should the nurse take?

  1. A
    Proceed with the medication administration to maintain therapeutic blood levels and document the laboratory results.
  2. B
    Increase the rate of the client's primary intravenous fluids to protect the kidneys before giving the dose.
  3. C
    Bypass the electronic barcode scanning system to ensure the medication is given exactly at the scheduled time.
  4. Withhold the upcoming dose of the medication and immediately communicate the laboratory findings to the registered nurse.Answer

Answer

The correct action is to withhold the upcoming dose of the medication and immediately communicate the laboratory findings to the registered nurse.
The correct action is to withhold the medication and report the findings. Gentamicin is an aminoglycoside antibiotic that is notoriously nephrotoxic. The client's serum creatinine level has abruptly increased from 1.0 mg/dL to 2.9 mg/dL, strongly indicating acute kidney injury. Giving another dose of gentamicin could cause further, potentially irreversible, renal damage. Within the scope of practice, the practical nurse must recognize this critical change, withhold the harmful agent, and escalate the information to the registered nurse or provider for a change in the treatment plan.

Step-by-Step Solution

1
Analyze the client's laboratory results.
The serum creatinine is 2.9 mg/dL, which is significantly higher than the normal range (0.6-1.2 mg/dL) and the baseline of 1.0 mg/dL.
Identifying abnormal laboratory values is critical before administering medications, especially those cleared by the kidneys.
2
Identify the properties of the prescribed medication.
Gentamicin is an aminoglycoside antibiotic known for its potential nephrotoxic side effects.
Understanding the adverse effects of medications helps the nurse anticipate complications.
3
Determine the appropriate nursing intervention based on the practical nurse scope of practice.
The nurse must withhold the nephrotoxic drug and escalate the critical laboratory finding to the registered nurse or healthcare provider.
Administering the medication could worsen kidney injury, and the practical nurse must report significant changes in client status to the supervising RN.

Key Concept

Recognizing nephrotoxicity and escalating critical laboratory values prior to medication administration.
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