Question

Difficulty: EasyDepressive Disorders

Match each clinical presentation to the most appropriate depressive disorder subtype or related diagnosis.

  • A 35-year-old man describes a two-year history of chronically low mood, fatigue, and poor self-esteem, stating 'I have just always been a sad person.'Persistent Depressive Disorder (Dysthymia)
  • A 24-year-old woman with a two-month history of severe depression reports sleeping 14 hours a day, significant weight gain, and a heavy, weighted feeling in her limbs.Major Depressive Disorder with atypical features
  • A 50-year-old man with severe anhedonia, early morning awakening, and a 15-lb weight loss over one month also reports hearing voices telling him he is 'rotten inside.'Major Depressive Disorder with psychotic features
  • A 29-year-old woman reports profound sadness, irritability, and breast tenderness that begin a week prior to her menses and resolve completely a few days after onset.Premenstrual Dysphoric Disorder

Answer

The correct matches align classic clinical features with their corresponding specific depressive disorder subtypes.
Each clinical vignette provides classic, textbook symptoms that uniquely define a specific depressive disorder or specifier. Matching them correctly requires knowledge of the DSM-5 criteria for Persistent Depressive Disorder (duration > 2 years), MDD with atypical features (hypersomnia, hyperphagia, leaden paralysis), MDD with psychotic features (delusions/hallucinations during a depressive episode), and Premenstrual Dysphoric Disorder (luteal phase symptom onset).

Step-by-Step Solution

1
Analyze the chronological duration and severity of the first presentation.
Two years of chronic, mild-to-moderate low mood without prolonged symptom-free periods.
This timeline differentiates Persistent Depressive Disorder from episodic Major Depressive Disorder.
2
Evaluate the specific vegetative symptoms in the second presentation.
Increased sleep, increased appetite/weight, and leaden paralysis are identified.
These reverse vegetative symptoms define the 'atypical features' specifier for MDD.
3
Identify the presence of perceptual disturbances in the third presentation.
Auditory hallucinations accompanying severe depression are noted.
Hallucinations occurring in the context of a major depressive episode establish the 'psychotic features' specifier.
4
Examine the temporal relationship of symptoms in the fourth presentation.
Symptoms are exclusively present in the late luteal phase and resolve with menses.
This cyclical pattern is the diagnostic core of Premenstrual Dysphoric Disorder.

Key Concept

Clinical differentiation of depressive disorder subtypes based on duration, specifiers, and temporal patterns.
Estimated Time:1m 0s
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