Question

Difficulty: EasyGastroenterology and Hepatology

Match each classic clinical presentation with its most likely esophageal diagnosis.

  • A 45-year-old patient with dysphagia to both solids and liquids, regurgitation of undigested food, and a 'bird's beak' appearance on a barium swallow study.Achalasia
  • A 60-year-old patient with a long history of untreated gastroesophageal reflux disease who now reports progressive dysphagia initially to solid foods, accompanied by unintentional weight loss.Esophageal adenocarcinoma
  • A 35-year-old patient presenting with severe, retrosternal chest pain and subcutaneous emphysema in the neck following multiple episodes of forceful retching.Boerhaave syndrome
  • A 40-year-old patient presenting with episodic, severe, non-cardiac chest pain and a 'corkscrew' appearance on a barium swallow study.Diffuse esophageal spasm

Answer

The patient with a 'bird's beak' appearance matches Achalasia. The patient with chronic GERD and progressive dysphagia matches Esophageal adenocarcinoma. The patient with transmural rupture following forceful vomiting matches Boerhaave syndrome. The patient with a 'corkscrew' esophagus matches Diffuse esophageal spasm.
Each clinical vignette provides pathognomonic features for a specific esophageal pathology, allowing direct diagnosis based on classic illness scripts expected for the exam.

Step-by-Step Solution

1
Analyze the first clinical vignette describing dysphagia to solids and liquids with a 'bird's beak' appearance.
Identified as Achalasia.
Achalasia is characterized by loss of primary peristalsis and failure of lower esophageal sphincter relaxation, leading to this classic radiologic finding.
2
Analyze the second vignette describing progressive dysphagia to solids and weight loss in a patient with chronic GERD.
Identified as Esophageal adenocarcinoma.
Chronic GERD is a major risk factor for Barrett's esophagus, which can transform into adenocarcinoma, typically presenting with mechanical obstruction.
3
Analyze the third vignette describing severe chest pain and subcutaneous emphysema after forceful retching.
Identified as Boerhaave syndrome.
Transmural esophageal rupture allows air to escape into the mediastinum and subcutaneous tissues, causing pneumomediastinum and crepitus.
4
Analyze the fourth vignette describing episodic chest pain and a 'corkscrew' esophagus.
Identified as Diffuse esophageal spasm.
Simultaneous, uncoordinated esophageal contractions create the classic 'corkscrew' appearance on a contrast swallow study.

Key Concept

Classic clinical presentations and radiologic findings of major esophageal disorders.
Rate this question