During morning rounds, the clinical team reviews the status of a patient who was hospitalized four days ago due to massive ascites and lower extremity edema. The patient has long-standing cirrhosis secondary to chronic hepatitis C virus infection. Despite medication compliance prior to admission, his weight had increased significantly over the preceding month. Current vital signs include a temperature of (), blood pressure of , and heart rate of . Physical examination reveals a tensely distended abdomen with a positive fluid wave and bilateral pitting edema extending to the thighs. The lungs are clear to auscultation. Recent laboratory values show a serum sodium of , serum potassium of , serum bicarbonate of , blood urea nitrogen of , and serum creatinine of (baseline was three weeks prior). A diagnostic paracentesis performed upon admission showed an absolute neutrophil count of . Urinalysis demonstrates no red blood cells, white blood cells, or casts, and the urine sodium concentration is . Renal ultrasonography reveals normal renal architecture without obstruction. Over the past 48 hours, all diuretic therapy was withheld, and the patient was administered intravenous albumin at per day. Today, his serum creatinine remains elevated at . Which of the following is the most appropriate next step in management?
- Administration of midodrine and octreotideAnswer
- BComputed tomography of the abdomen with intravenous contrast
- CIntravenous furosemide infusion
- DIntravenous piperacillin-tazobactam
- EIntravenous sodium bicarbonate