Question

Difficulty: MediumGastroenterology and Hepatology

A 68-year-old man is admitted to the hospital with a 2-day history of progressively worsening, crampy abdominal pain, abdominal distension, and multiple episodes of bilious vomiting. He reports not having passed flatus or stool for the past 24 hours. His past medical history is significant for hypertension and an open appendectomy 15 years ago.

Vital signs are:
Temperature: 37.2∘C37.2^\circ\text{C} (99.0∘F99.0^\circ\text{F})
Blood pressure: 105/65 mmHg105/65\text{ mmHg}
Heart rate: 110/min110/\text{min}
Respiratory rate: 18/min18/\text{min}

Physical examination reveals a markedly distended and tympanitic abdomen. Bowel sounds are high-pitched and hyperactive. There is diffuse, mild tenderness to palpation, but no rebound tenderness or abdominal wall rigidity.

Laboratory results show:
Leukocyte count: 9,500/mm39,500/\text{mm}^3
Serum sodium: 138 mEq/L138\text{ mEq/L}
Serum potassium: 3.2 mEq/L3.2\text{ mEq/L}
Serum chloride: 96 mEq/L96\text{ mEq/L}
Serum bicarbonate: 29 mEq/L29\text{ mEq/L}
Blood urea nitrogen: 48 mg/dL48\text{ mg/dL}
Serum creatinine: 1.9 mg/dL1.9\text{ mg/dL} (Baseline: 1.0 mg/dL1.0\text{ mg/dL})
Lactic acid: 1.1 mmol/L1.1\text{ mmol/L} (Normal: 0.5−2.2 mmol/L0.5 - 2.2\text{ mmol/L})

Upright abdominal radiography reveals multiple dilated loops of small intestine with prominent air-fluid levels and an absence of colonic gas.

Which of the following is the most appropriate next step in the management of this patient?

  1. Placement of a nasogastric tube and intravenous fluid resuscitationAnswer
  2. B
    Immediate exploratory laparotomy
  3. C
    Empirical administration of broad-spectrum intravenous antibiotics
  4. D
    Intravenous administration of furosemide
  5. E
    Intravenous administration of sodium bicarbonate

Answer

Placement of a nasogastric tube and intravenous fluid resuscitation
The correct intervention is the placement of a nasogastric tube and intravenous fluid resuscitation. This patient presents with classic signs of a small bowel obstruction (SBO) secondary to adhesions from a prior appendectomy. Crucially, his presentation is 'uncomplicated', meaning there are no clinical signs of bowel ischemia or strangulation (which would present as fever, continuous severe pain, peritoneal signs, profound leukocytosis, or elevated lactate). In uncomplicated SBO, the standard of care is conservative management with bowel rest, gastrointestinal decompression via a nasogastric tube, and aggressive intravenous fluid replacement to correct the hypovolemia and prerenal acute kidney injury caused by vomiting and third-spacing of fluids.

Step-by-Step Solution

1
Diagnose the primary condition based on history, physical exam, and imaging.
The patient has an acute small bowel obstruction (SBO), supported by crampy abdominal pain, vomiting, lack of flatus, high-pitched bowel sounds, and radiographic evidence of dilated small bowel loops with air-fluid levels.
Establishing the clinical diagnosis is the required first step before determining the severity and management plan.
2
Assess for complications such as bowel ischemia, strangulation, or perforation.
The patient lacks fever, significant leukocytosis, lactic acidosis, or peritoneal signs (no rebound or guarding).
The presence of complications dictates whether immediate surgery is required versus a trial of conservative medical management.
3
Evaluate the patient's hemodynamic and fluid status.
Tachycardia, borderline hypotension, elevated BUN:creatinine ratio (>20:1), and hypokalemic metabolic alkalosis indicate severe intravascular volume depletion.
Vomiting and third-spacing of fluids into the distended bowel rapidly lead to hypovolemia and pre-renal acute kidney injury.
4
Select the appropriate intervention based on the uncomplicated SBO and volume status.
The patient requires immediate gastrointestinal decompression and volume replacement.
Nasogastric tube placement prevents further vomiting and aspiration, while IV fluids restore renal perfusion and hemodynamics.

Key Concept

The initial management of acute, uncomplicated small bowel obstruction consists of conservative measures: nil per os (NPO), nasogastric tube decompression, and aggressive intravenous fluid resuscitation.
Estimated Time:1m 30s
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