A 68-year-old woman presents to the emergency department with sudden-onset, severe pain in her right lower extremity that began 2 hours ago. On physical examination, the right foot is pale, cold, and pulseless. She is unable to wiggle her toes, and sensation to light touch is absent over the dorsum of the foot. Her blood pressure is 145/90 mmHg, and her heart rate is 110/min with an irregularly irregular rhythm. Which of the following are the most appropriate immediate steps in the management of this patient? (Select all that apply)
- Immediate administration of an intravenous unfractionated heparin bolus and continuous infusionAnswer
- Emergent consultation with vascular surgery for operative embolectomyAnswer
- CDischarge home with a prescription for oral rivaroxaban and outpatient vascular follow-up
- DWithholding systemic anticoagulation until magnetic resonance angiography (MRA) confirms the diagnosis
- EGraded treadmill exercise testing with ankle-brachial index (ABI) measurements
Answer
The correct immediate steps are the immediate administration of an intravenous unfractionated heparin bolus and continuous infusion, alongside an emergent consultation with vascular surgery for operative embolectomy.
This patient's presentation of sudden-onset pain, pallor, pulselessness, paresthesia (sensory loss), and paralysis (motor weakness) in the setting of an irregularly irregular heart rhythm (atrial fibrillation) is highly diagnostic of acute limb ischemia. The embolus likely originated from the heart. The presence of sensory and motor deficits indicates a severely threatened limb (Rutherford category IIb). For a threatened limb, the standard of care is to immediately initiate systemic anticoagulation with intravenous unfractionated heparin to prevent further propagation of the clot. Concurrently, an emergent vascular surgery consultation must be obtained for operative embolectomy or catheter-directed revascularization. Any delay in restoring perfusion increases the risk of irreversible tissue damage and subsequent amputation.
Step-by-Step Solution
Key Concept
Patients with acute limb ischemia presenting with sensory or motor deficits have a threatened limb, which requires immediate systemic anticoagulation with intravenous heparin and emergent surgical revascularization.
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