Question

Difficulty: MediumInterpreting Imaging Results

A 76-year-old male patient arrives at the emergency department reporting excruciating, sudden-onset abdominal pain that began three hours prior to evaluation. His past medical history is notable for hypertension, type 2 diabetes mellitus, and chronic atrial fibrillation, though he admits to frequently missing doses of his oral anticoagulant. His temperature is 37.9°C (100.2°F), blood pressure is 105/65 mm Hg, pulse is 122/min and irregularly irregular, and respirations are 24/min. On physical examination, the patient appears in distress and is writhing in bed. The abdomen is mildly distended and diffusely tender, but there is no rigidity or rebound tenderness. Bowel sounds are hypoactive. Laboratory studies show a leukocyte count of 19,500/mm³ and a serum lactate level of 4.8 mmol/L. A contrast-enhanced CT scan of the abdomen and pelvis reveals a focal filling defect in the proximal superior mesenteric artery. Additional imaging findings include diminished mucosal enhancement in the distal jejunum and small, linear branching lucencies in the periphery of the liver. Based on the interpretation of these imaging findings, which of the following is the most appropriate next step in management?

  1. Emergent exploratory laparotomyAnswer
  2. B
    Catheter-directed thrombolysis
  3. C
    Intravenous heparin infusion and observation
  4. D
    Magnetic resonance angiography of the abdomen
  5. E
    Percutaneous endovascular angioplasty and stenting

Answer

Emergent exploratory laparotomy
The correct answer is emergent exploratory laparotomy. This patient has acute mesenteric ischemia, likely due to an arterial embolus originating from his atrial fibrillation. The CT scan demonstrates a filling defect in the superior mesenteric artery alongside diminished mucosal enhancement and linear branching lucencies in the periphery of the liver. These hepatic lucencies represent portal venous gas, which, in this clinical context, is a radiologic hallmark of transmural bowel infarction and necrosis. When imaging indicates irreversible bowel necrosis, medical management or endovascular revascularization alone is inadequate and potentially fatal. The patient requires immediate exploratory laparotomy to resect the nonviable bowel segments and potentially undergo an open surgical embolectomy.

Step-by-Step Solution

1
Identify the primary diagnosis based on the clinical presentation.
Severe abdominal pain out of proportion to physical exam findings in a patient with atrial fibrillation suggests acute mesenteric ischemia.
Atrial fibrillation increases the risk of arterial thromboembolism, which most commonly lodges in the superior mesenteric artery.
2
Interpret the specific imaging findings described in the stem.
The CT scan shows an SMA filling defect (confirming ischemia) and linear branching lucencies in the liver periphery, which represent portal venous gas.
Portal venous gas occurs when mucosal integrity is compromised due to transmural bowel necrosis, allowing intraluminal gas to enter the portal venous circulation.
3
Determine the appropriate management based on the interpretation of the imaging.
Select emergent exploratory laparotomy.
The presence of radiologic signs of bowel infarction (portal venous gas and lack of mucosal enhancement) is an absolute indication for immediate surgical resection rather than medical or endovascular therapy.

Key Concept

Recognition of portal venous gas on CT imaging as a sign of transmural bowel infarction in acute mesenteric ischemia, which necessitates emergent surgical intervention.
Estimated Time:1m 15s
Rate this question