In 1928, British bacteriologist Frederick Griffith conducted a landmark experiment investigating Streptococcus pneumoniae, the bacterium responsible for pneumonia. Griffith utilized two distinct strains: the virulent 'S' (smooth) strain, enclosed in a protective polysaccharide capsule that shielded it from the host's immune system, and the non-virulent 'R' (rough) strain, which lacked this capsule. When Griffith injected mice with heat-killed S-strain bacteria, the mice survived, confirming that dead bacteria alone were harmless. However, when heat-killed S-strain bacteria were combined with living R-strain bacteria and injected into mice, the animals succumbed to pneumonia, and living S-strain bacteria were subsequently isolated from their blood. Griffith concluded that a non-living 'transforming principle' had passed from the dead S-strain bacteria to the living R-strain bacteria, permanently endowing them with the ability to synthesize the protective capsule. Although Griffith did not identify the chemical identity of this transforming principle, his findings established that genetic traits could be horizontally transferred between bacterial strains.
According to the passage, which of the following statements regarding Griffith's 1928 experiment are explicitly supported by the text?
- Mice injected exclusively with heat-killed S-strain bacteria survived the procedure.Cevap
- BThe protective polysaccharide capsule of the R-strain bacterium was chemically destroyed by heat prior to injection.
- Griffith succeeded in isolating living S-strain bacteria from mice exposed to a mixture of live R-strain and heat-killed S-strain bacteria.Cevap