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Zorluk: ZorMendel's First Law and Monohybrid Inheritance

In monohybrid inheritance experiments involving guinea pig coat color, where the allele for black fur (BB) is completely dominant over the allele for white fur (bb), match each specified parental cross or test cross scenario on the left with its corresponding phenotypic or genotypic outcome in the offspring on the right.

  • Cross between a heterozygous black guinea pig (BbBb) and a white guinea pig (bbbb)A 1:11:1 phenotypic and genotypic ratio (50%50\% heterozygous black, 50%50\% homozygous white)
  • Cross between two heterozygous black guinea pigs (Bb×BbBb \times Bb) yielding a total of 160 offspringExpected phenotypic distribution of approximately 120 black fur and 40 white fur offspring
  • A test cross of a dominant black guinea pig that produces 100% black offspring across multiple littersIndicates the tested parent is homozygous dominant (BBBB), as no recessive allele was contributed by that parent
  • Cross between pure-breeding black (BBBB) and pure-breeding white (bbbb) parents to produce the F1F_1 generation100% uniform heterozygous genotype (BbBb) exhibiting the black fur phenotype

Cevap

The correct pairings match each monohybrid inheritance scenario to its precise Mendelian ratio or outcome: (1) Heterozygous black crossed with white matches the 1:1 genotypic and phenotypic ratio; (2) Two heterozygous black parents producing 160 offspring matches 120 black and 40 white offspring (3:1 ratio); (3) A test cross producing 100% dominant offspring confirms a homozygous dominant parent (BB); and (4) Crossing pure-breeding parents yields 100% uniform heterozygous F1 offspring.
Each cross directly demonstrates a fundamental aspect of Mendel's First Law. Heterozygote ×\times homozygous recessive gives a 1:11:1 ratio; two heterozygotes produce a 3:13:1 phenotypic ratio (120:40 out of 160); a test cross yielding zero recessive offspring confirms homozygous dominance; and contrasting pure lines produce uniform F1F_1 heterozygotes.

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1
Analyze the cross between BbBb and bbbb
Gametes: Parent 1 produces BB and bb in equal proportion (1:11:1), Parent 2 produces only bb. Offspring genotypes: 12Bb\frac{1}{2} Bb (black fur) and 12bb\frac{1}{2} bb (white fur).
Mendel's Law of Segregation dictates that alleles segregate during gamete formation so that each gamete carries only one allele for each gene.
2
Calculate expected offspring numbers for Bb×BbBb \times Bb with total N=160N = 160
Monohybrid phenotypic ratio is 33 dominant : 11 recessive. Dominant count =34×160=120= \frac{3}{4} \times 160 = 120; Recessive count =14×160=40= \frac{1}{4} \times 160 = 40.
A monohybrid cross of two heterozygotes generates a genotypic ratio of 1BB:2Bb:1bb1 BB : 2 Bb : 1 bb, which simplifies to a 3:13:1 phenotypic ratio under complete dominance.
3
Evaluate the test cross of an unknown black parent with a recessive bbbb parent
If the parent were BbBb, white offspring would appear in approximately 50%50\% of cases. Since 100%100\% of offspring are black, the unknown parent must be homozygous dominant (BBBB).
A test cross uses a known homozygous recessive individual to reveal whether an organism expressing a dominant trait is homozygous or heterozygous.
4
Determine the outcome of crossing homozygous contrasting parents (BB×bbBB \times bb)
All F1F_1 offspring receive BB from the black parent and bb from the white parent, making 100%100\% of the F1F_1 generation heterozygous (BbBb).
This illustrates Mendel's principle of uniformity in the F1F_1 generation when crossing pure lines.

Anahtar Kavram

Mendel's Law of Segregation and Monohybrid Inheritance Ratios
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