A medical researcher is evaluating the relationship between the class of oral antidiabetic medication prescribed and the incidence of major adverse cardiovascular events (MACE) in a retrospective cohort of 1,250 patients with type 2 diabetes. The medication classes are categorized as SGLT2 inhibitors (), GLP-1 receptor agonists (), and DPP-4 inhibitors (). The cardiovascular outcomes over the study period are classified into three mutually exclusive categories: myocardial infarction (), ischemic stroke (), and no MACE ().
The researcher plans to use a Pearson chi-square test to determine if the choice of medication is independent of cardiovascular outcomes. A key assumption of this test is that no more than 20% of the expected cell frequencies are less than 5.
Under the null hypothesis of no association, what is the expected count of patients who were prescribed a GLP-1 receptor agonist and subsequently experienced a myocardial infarction? (Enter your answer as a whole number).
Cevap: 72 patients