Match each clinical study design and variable configuration with the most appropriate inferential statistical test used for data analysis.
- Comparing mean serum cholesterol levels (a normally distributed continuous variable) among three independent patient cohorts receiving different statin therapies.One-way Analysis of Variance (ANOVA)
- Comparing the incidence of postoperative wound infections (a nominal categorical variable) between patients receiving prophylactic antibiotics versus placebo.Chi-square test
- Comparing median urinary protein excretion (a highly skewed continuous variable) between patients with diabetic nephropathy and healthy controls.Mann-Whitney U test
- Evaluating changes in mean tumor volume (a normally distributed continuous variable) within the same group of oncology patients before and after a targeted 12-week chemotherapy regimen.Paired t-test
Cevap
The correct matches align three cohorts to ANOVA, categorical infection incidence to the Chi-square test, skewed protein levels to the Mann-Whitney U test, and paired before-and-after tumor volumes to the Paired t-test.
Each study design correctly matches with the statistical test that accommodates its specific combination of variables, group numbers, and data distribution.
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Anahtar Kavram
Selection of the appropriate inferential statistical test is determined by the number of comparison groups, the independence of those groups (paired vs. unpaired), the data type (continuous vs. categorical), and the underlying distribution (normal vs. skewed).