Soru

An occupational health physician evaluates a 28-year-old woman who is preparing to begin employment as a clinical laboratory technician, a role that involves handling human blood samples. She has a medical history of severe plaque psoriasis, which has been well controlled since initiating treatment with subcutaneous adalimumab six months ago. She has no other medical conditions. She has never smoked cigarettes and consumes alcohol occasionally. Her last cervical cancer screening with cytology was one year ago and was normal. Physical examination today reveals normal vital signs and clear skin with faint residual hyperpigmentation on the extensor surfaces. A review of her childhood immunization records confirms completion of the standard pediatric series, including two doses of the measles, mumps, and rubella vaccine. Pre-employment serological testing indicates a negative varicella-zoster virus IgG antibody and a negative hepatitis B surface antibody (anti-HBs). The patient states she never had chickenpox as a child. Which of the following is the most appropriate immunization strategy for this patient?