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Zorluk: OrtaSex Determination and Sex-Linked Traits

A color-blind man marries a phenotypically normal woman whose mother was color-blind. What is the probability that any female child born to this couple will be color-blind?

  1. A
    25%25\%
  2. 50%50\%Cevap
  3. C
    75%75\%
  4. D
    100%100\%

Cevap

The probability that a female child born to this couple will be color-blind is 50%50\%.
The father has the genotype XcYX^c Y and passes his XcX^c chromosome to all female children. The mother is phenotypically normal but carries the allele from her color-blind mother, making her genotype XCXcX^C X^c. Half of her egg cells carry XCX^C and half carry XcX^c. Therefore, 50%50\% of female offspring receive XcX^c from both parents (XcXcX^c X^c) and are color-blind.

Adım Adım Çözüm

1
Determine the genotypes of the parents.
The father is color-blind (XcYX^c Y). The mother is phenotypically normal but her mother was color-blind (XcXcX^c X^c), meaning the mother must be a carrier (XCXcX^C X^c).
Sex-linked recessive traits on the X chromosome require identifying maternal and paternal allele contributions.
2
Perform a genetic cross for female offspring.
Female children inherit XcX^c from the father and either XCX^C or XcX^c from the mother, resulting in genotypes XCXcX^C X^c (carrier) and XcXcX^c X^c (color-blind) in a 1:11:1 ratio.
Determining the phenotypic ratio specifically among female offspring requires considering only the XX combinations.
3
Calculate the probability for female offspring.
11 out of 22 female children (50%50\%) will have the XcXcX^c X^c genotype and express color blindness.
The question asks specifically for the probability among female children.

Anahtar Kavram

Sex-Linked Inheritance and Female Phenotypic Probability
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