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Zorluk: OrtaSex Determination and Sex-Linked Traits

In *Drosophila melanogaster*, eye color is an X-linked trait where red eye color (XRX^R) is dominant over white eye color (XrX^r). If a heterozygous red-eyed female (XRXrX^R X^r) is crossed with a white-eyed male (XrYX^r Y), what is the probability that a female offspring from this cross will express the white-eye phenotype?

  1. A
    25%
  2. 50%Cevap
  3. C
    75%
  4. D
    100%

Cevap

50%
The female parent donates either XRX^R or XrX^r with equal probability (50% each), while the male parent donates an XrX^r chromosome to all female offspring. As a result, 50% of the female offspring inherit XRXrX^R X^r (red-eyed) and 50% inherit XrXrX^r X^r (white-eyed).

Adım Adım Çözüm

1
Determine parental genotypes and gamete contributions.
Female genotype is XRXrX^R X^r (gametes: XRX^R and XrX^r); Male genotype is XrYX^r Y (gametes: XrX^r and YY).
The gene for eye color in Drosophila is located on the X chromosome.
2
Construct the genetic cross to find offspring genotypes.
Offspring genotypes are XRXrX^R X^r (red-eyed female), XrXrX^r X^r (white-eyed female), XRYX^R Y (red-eyed male), and XrYX^r Y (white-eyed male). Each genotype represents 25% of total offspring.
Combining maternal and paternal gametes yields four equally likely genotypic outcomes.
3
Restrict the calculation specifically to female offspring.
Female offspring genotypes are XRXrX^R X^r and XrXrX^r X^r. One out of two female offspring (XrXrX^r X^r) has white eyes, giving a probability of 12=50%\frac{1}{2} = 50\%.
The question specifically asks for the probability among female offspring, not among all offspring.

Anahtar Kavram

X-linked recessive inheritance and gender-restricted offspring probability calculations
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