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Zorluk: KolayGynecologic Oncology

Match each of the following gynecologic neoplasms with the serum tumor marker that is most characteristically elevated in affected patients.

  • Endodermal sinus (yolk sac) tumorAlpha-fetoprotein (AFP)
  • Granulosa cell tumorInhibin
  • DysgerminomaLactate dehydrogenase (LDH)
  • Serous cystadenocarcinomaCancer antigen 125 (CA-125)

Cevap

Endodermal sinus (yolk sac) tumor matches with Alpha-fetoprotein (AFP); Granulosa cell tumor matches with Inhibin; Dysgerminoma matches with Lactate dehydrogenase (LDH); Serous cystadenocarcinoma matches with Cancer antigen 125 (CA-125).
Each gynecologic neoplasm is associated with a specific, characteristic tumor marker used for diagnosis and monitoring of disease. Endodermal sinus tumors produce AFP, granulosa cell tumors produce inhibin, dysgerminomas frequently present with elevated LDH, and epithelial tumors such as serous cystadenocarcinoma are monitored with CA-125.

Adım Adım Çözüm

1
Identify the tumor marker for endodermal sinus (yolk sac) tumor.
Alpha-fetoprotein (AFP)
Yolk sac tumors are malignant germ cell tumors that characteristically secrete high levels of AFP.
2
Identify the tumor marker for granulosa cell tumor.
Inhibin
Granulosa cell tumors are sex cord-stromal tumors that typically secrete estrogen and inhibin, making inhibin a useful marker for diagnosis and monitoring.
3
Identify the tumor marker for dysgerminoma.
Lactate dehydrogenase (LDH)
Dysgerminomas are the most common malignant ovarian germ cell tumors and are typically associated with elevated LDH levels.
4
Identify the tumor marker for serous cystadenocarcinoma.
Cancer antigen 125 (CA-125)
Serous cystadenocarcinoma is the most common malignant epithelial ovarian cancer, which is characteristically monitored using serum CA-125 levels.

Anahtar Kavram

Gynecologic neoplasms and their associated serum tumor markers
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Konular

Gynecologic Oncology

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