Soru

A $38$-year-old man with a history of HIV infection presents to the emergency department with a $2$-week history of progressively worsening headache, fever, and confusion. He has not taken antiretroviral therapy for the past year. Vital signs are temperature $38.8^\circ\text{C}$ ($101.8^\circ\text{F}$), pulse $105/\text{min}$, respirations $16/\text{min}$, and blood pressure $110/70\text{ mmHg}$. Physical examination shows lethargy, nuchal rigidity, and bilateral papilledema. A head CT scan without contrast reveals no focal lesions, mass effect, or hydrocephalus. Laboratory studies show a CD4 T-lymphocyte count of $45/\text{mm}^3$ and a serum sodium level of $131\text{ mEq/L}$. Lumbar puncture is performed. Cerebrospinal fluid (CSF) analysis shows an opening pressure of $360\text{ mm H}_2\text{O}$. CSF leukocyte count is $150/\text{mm}^3$ ($85\%$ lymphocytes), protein is $120\text{ mg/dL}$, and glucose is $30\text{ mg/dL}$. India ink preparation reveals encapsulated yeast cells. Which of the following pharmacologic interventions are indicated as part of this patient's immediate management? (Select all that apply)